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Koch's postulates

Mar 28, 2004

What are "Koch's postulates" and why do those misguided scientists who say it's not proven that HIV causes AIDS cite them to question the validity of HIV antibody and molecular/PCR testing?

Is it that HIV testing does in fact meet Koch's postulates or that the postulates need to be adjusted to reflect developments in antibody and molecular/PCR testing? And wouldn't isolation of HIV by viral co-culture fulfill Koch's postulates?

Thank you.

Response from Dr. Holodniy

Basically the postulates are as follows: 1. An organism can be isolated from a host suffering from the disease and 2. The organism can be cultured in the laboratory and 3. The organism causes the same disease when introduced into another host and 4. The organism can be re-isolated from that host then The organism is the cause of the disease and the disease is an infectious disease.

There is an implicit assumption in step three, namely that the other host must have a genetic make-up that causes it to react to the organism in the same way as the original host.

I leave it to you to decide whether HIV fullfills the criteria.

How high can cd4 go up
acute simultaneous co-infection viral load

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