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Free Testosterone Level
Feb 8, 2004

Thank you for this website and forum. What is the difference between free and total testosterone lab values, what are normal values? What do these levels mean in relation to HIV physiology? Signed ~ Kansas Prairie Man

Response from Dr. Holodniy

The total testosterone is the total amount of testosterone in the blood, 90% or more which is bound up by other proteins in the blood and therefore not biologically active. The free testosterone level is a measure of the testosterone that is available to the cells. The total is usually in the range from 350-1000 ng/dL and the free testosterone is in the range of 50-250 pg/ml. Levels can decrease just with age and with advancing HIV disease. Lower levels are not just associated with decreased libido, but with decreasing muscle mass.



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