|Conflicting PCR tests: different primers and different results!
Jan 18, 2004
Dr. Holodniy, I know this may not be an easy question, but can you please try to help me? I tested positive twice at a very reputable Lab on an HIV-2 PCR DNA with primers for GAG, but tested negative twice at another very reputable Lab on their HIV-2 PCR DNA test that uses LTR primers. Antibody test inconclusive.
So, which is the better, more sensitive and specific test for detecting HIV-2 virus...the one with GAG or the one with LTR primers? (I was told that these tests look for more conserved regions of the virus, so is LTR or GAG more conserved and reliable for diagnosis?). I really need to resolve this, especially since I have continued viral symptoms and a low CD4/CD8 ratio. Liver enzymes also high.
| Response from Dr. Holodniy
I don't know the answer to that question.
Get Email Notifications When This Forum Updates or Subscribe With RSS
- What Is The Difference Between Pcr And Nat?
- Difference Between Hiv And Aids Symptoms
- What Is The Name Of Different Hiv Tests?
- How Long Does It Take For A Bacterial Vaginosis To Harm You?
- What Causes Trichomoniasis Vaginitis?
- What Can I Do For My Immune System To Keep From Getting Shingles Again?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.