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Viral Load Undetectable but CD4s Keep Dropping

Oct 11, 2003


I had some initial labs done a few months ago after being tested hiv poz in May:

June CD4 389 Viral Load 1,700 July CD4 310 Viral Load 1,300 Aug CD4 289 Viral Load 1,100

Since my CD4s kept dropping below a 350 mark, I opted to start treatment a month ago on a once a day regimen of sustiva/emtriva and viread

Just got my one month labs done and my viral load is undetectable BUT my CD4s contune to drop..

This time to 230.

My doc said that usually the T-Cell count starts to rise after treatment. I thought that with such a low viral load to begin with ,and now an undetectable one, I would see some improvement in immune function.

SHould I be concerned? What could this mean?

Response from Dr. Holodniy

It would also be helpful to know your CD4 percentages over time, and whether we are seeing an increase with treatment. I would not be too concerned just one month after starting treatment. That is a very potent regimen, I suspect your CD4 counts will pick up soon.

Block gp120 on CD4 instead of attacking HIV?
How rare is it for treatment naive HIVers to have an undetectable VL a year or more after infection?

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