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HIV-2 CD4/CD8 ratio
Jun 22, 2003

Dr. Holodniy,

Is it true that low CD4/CD8 ratios, but more normal CD4 counts are very typical of HIV-2 infection (compared to HIV-1, where there are usually both low CD4 numbers and CD4/CD8 ratios)?

I had read that there is a slower decline in CD4 cells with HIV-2 infection, but never knew that it was associated with a simultaneously low CD4/CD8 ratio.

Thanks.

Response from Dr. Holodniy

You are correct that there is a slower decline in CD4 count with HIV-2 infection.



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