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effect of anti-coagulant
May 18, 2003

Dr Holodniy, i am not sure if this is the right forum but i do realise you have a lot of expertise in the field of labs. i wanted find out whether CPD(the anti-coagulant used in blood banks) has any inhibitory effect on viral load values like heparin and whether mixing it with EDTA would alter the viral load significantly.

Response from Dr. Holodniy

ACD or CPD (citrate) will not affect viral load values, like heparin can in some viral load tests. Likewise, EDTA does not affect viral load values. I have no experience in mixing blood samples that have been collected in citrate and EDTA and then mixed together. My impression is that since niether individually affects the result, the combination would not either.



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