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recombinant B/F
Mar 15, 2003

I was infected in Thailand but genotype tests shows my virus as recombinant B/F. B I understand of course but have you encountered subtype F before?? What implications might this have for disease progression or treatment?

My vl has gone from 7,000 at 3 months to 100,000 at 6mo while Tcells have gone from 620/26 to 560/28 (at least the percentage has increased). I don't find this sudden deterioration too comfortable! Please comment.

Response from Dr. Holodniy

There is acutally lots of subtype F and B/F mixtures in South America. We don't have enough data to know whether progression rates are different, but treatment response appears to be similar to subtype B.



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