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Neg Partner w/ Questions
Mar 9, 2003

We are a serodicordant couple. My partner started meds one year ago and responded quickly (v/l undetectable, high C counts) with few side effects. He has switched to offset unwanted sides (hair loss, mood swings) twice, the latest about four months ago.

Now, one year on, his v/l has moved from undetectable to 75 to over 500 in a matter of three weeks of re-tests. His Cd4 count remains very high.

Should I be alarmed? It's not a topic that we easily and readily can discuss.

Response from Dr. Holodniy

This could be the result of "blipping", which is periodic appearance of virus in the blood, after which the viral load goes back down to undetectable. Alternatively, this could be the result of decreased adherence to the regimen or the development of resistance.



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