Sep 15, 2002
Mark, I read an article on today's newspaper that stated hiv is attracted to lipid tissues in the body, and is to blame for lipodistrophy. What a thing, ain't it? Why? Why is hiv attracted to lipids? Are they more to its liking than T-Cells, or is it its dessert? Do you think any decoy-strategy could be developed out of this discovery?
Response from Dr. Holodniy
Not sure what the context of this article was. The overwhelming majority of lipodystrophy cases have been associated with HIV medication use. However, there a small group (thus far) in whom lipodystrophy has developed in the absence of HIV meds. We are just beginning to understand the cellular mechanisms that cause this syndrome. Whether HIV triggers some directly in fat cells is not clearly known.
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