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Different variety of HIV strain C in India?
Mar 1, 2001

Dear Dr Holodniy. I have recently read an article over the internet, published in the Journal of Virology (1999). Scientists, who are investigating vaccine formation have discovered that HIV subtype C in India is somehow different from the other C strains worldwide. They found that "genes coding for proteins in the outer "envelope" of the "C" virus vary significantly" from other strains. Moreover some of the C subtype have been identified to be mosaic - blend of subtype C and A. The question what i have is: Will the current, up-to-date ELISA kits (for ex: Orto-Clinical diagnostics or Innogenetics)be sensitive to detect that variety of HIV strain C in India? Do other tests need to be considered for screening? Thank you very much for your reply.

Response from Dr. Holodniy

I guess you will have to call and ask Ortho.



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