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PCR RNA testing

Mar 1, 2001

If the new standard in PCR RNA testing is <50 copies, why are some of the reputable labs still using the test using <400 copies. While I realize that this test is not approved for diagnosis,wouldn't more recently infected (say within the last 3-4 months) be missed as their viral load could be <400 or would one's viral load in this scenario be much higher (in the absence of detectable antibodies)?

Response from Dr. Holodniy

Viral load levels will be much higher. The lower sensitivity levels are required to measure more effective treatment responses.

Hepatitis C Heterosexual transmission/viral load number
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