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Combination PCR RNA/ELISA
Mar 1, 2001

Is a PCR RNA likely to show a higher viral load shortly after infection (during ARS) or months later. I have heard that one's viral load will be highest shortly after infection and will decrease after a few months, thus making the PCR RNA a non-accurate test at that point in time. Also what would you say the negative predictive value of the combination of an ELISa (negative) at 3 months and PCR (<400) at 4 months would be? PLease answer!

Response from Dr. Holodniy

You are half correct. It is higher during ARS, but in almost all cases, remains positive months after.



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