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Infection and rate of progression

Feb 17, 2002

I was wondering if the amount of virus transmitted at infection has anything to do with the characteristics and evolution of the infection. A person infected because of a faulty condom as opposed to a person infected because of no condom may get much lower amounts of virus into her bloodstream, and thus might show less severe reactions and slower progression? (because, maybe the body has more time to "get used" to the virus, as it slowly progresses and grows to a critical amount, where the body reacts to it and produces antibodies???) Any data to that respect? Thanks for your comment

Response from Dr. Holodniy

That would be difficult to quantitate and there is likely to be no data. You would need to know the inoculum size at the time of infection.

HIV attacking central nervous system
high cd4 count low cd4

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