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RE: New Blood
Feb 17, 2002

I understand that hiv would not be eliminated using my saved blood (because there would be infected cells there). Nevertheless, if I save blood when it is not still deteriorated enough (normal CD4, CD8 to CD4 ratios, and minimum viral load), could that be of any help when my blood enters critical numbers? Would that work as sort of a biological "reset" button? Thanks.

Response from Dr. Holodniy

Hopefully you will never reach critical numbers with current effective treatment. Even in earlier disease, the argument regarding infected cells still holds. What you probably want to harvest and store are uninfected stem cells, which can then differentiate into t cells. This is the subject of current research, except that stem cells are being engineered in the lab and reinfused back into the patient where they are either resistant to infection or make more effective immune responses.



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