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no antibodies
Jan 2, 2001

Dear Doctor,

I was not tested until I had been HIV+ for about 14 yrs. Both Elisa and Western Blot were negative. Because of my symptoms an HIV antibodies PCR for HIV DNA was done.

It was positive.

Why weren't the other tests accurate??

Was it because my immune system was too depleted??

Any other reason??

Thank you.

Response from Dr. Holodniy

There are a handful of cases reported to the CDC, where people with AIDS, probably lost there antibodies due to a severe loss of B cells (which make the antibodies). These people were still HIV positive because their PCR or viral culture tests were positive.

MH



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