|Not becoming Resistant
Oct 2, 2000
Hey Doc: I am on Viracept+AZT+Epivir. I had told you I only take 400MG of AZT per day and not the typical 600MG that is consistent with the dosing in Combivir. You asked me why and my doctor seems to think that you don't need all that AZT in your blood as long as you remain undetectable, which so far I have. 2 questions: A) T cells won't budge above 312 from the 304 they were 5 months ago. Is it possible that they can suddenly soar up out of nowhere or is this my number? B)I throw up every couple of weeks from these meds and my doc tells me this could be a reason that I do not rise in T cells much. He says each time you gag and throw up that you are causing your body to use T cells, thinking that there is something to fight. One last thing. Are there people with viral loads like I had of 110,000 who stay undetectable on one regimen for more than 3 years at a clip? I have heard the higher the VL the less amount of time you may maintain your VL at <50. Just a few quick quesitons hopefully you have information on. Again, you are a gem of a person and I think you do people a great service with such optimism in a world of negativity.
| Response from Dr. Holodniy
A. You are probably going to stay in the 300s range, which is OK to keep you out of trouble from developing bad infections.
B. Never heard of vomiting keeping T cells down. There are in fact many people who started with viral loads > 100,000 who are now going on 4 years or longer of being undetectable. Adherence to the regimen is the main reason for success.
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