Dec 24, 2001
i have recently read that hiv requires co-receptors to bind and be engulfed in the bloodstream. is there any evidence that these coreceptors may be absent from certain parts of the body - for example, parts of the skin compared to mucous membranes? such evidence may explain why infection via mucousal membranes is high. thank you.
Response from Dr. Holodniy
Alternatively, another reason for infection via mucosal membranes is the large number of dendritic cells which process HIV and take it to the lymphnodes were rapid infection insues.
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