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haart therapy and hiv genes
Oct 25, 2009

Of the nine HIV genes, which one according to HAART therapy would be the most dangerous if it were to mutate?

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   Response from Dr. Holodniy

Almost all HIV drugs work on HIV enzymes (reverse transcriptase and protease) that are co-located in the HIV-1 pol gene. Mutations in the gene sequences coding for these enzymes are known to cause drug resistance and therefore failure of many HIV medication regimens.



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