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Undetectable VL , CD4 percentage dropped
Oct 18, 2009
Hi Doctor Holodniy,
I am on Atripla for the past 8 months. My CD4 rose steadily from 320, 16% before treatment to 488, 34% while my VL declined to undetectable levels from 28000. I just got my new test results, VL is still undetectable but CD4% dropped to 28% from 34% within the last 3 months, I don't have the absolute number yet due to a technical lab problem but I'm guessing it will be low as well given the sharp drop in percentage. My doctor is on vacation, I would like to get your opinion on this. Is it normal to see such sharp fall in CD4 percentage while still having undetectable VL levels?
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Response from Dr. Holodniy

That is a bit out of the range of normal CD4% variability, which is usually < 3%. I am not that concerned as your viral load remains undetectable. I don' think there is anything I would do at this point. I think your meds are working for you.
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