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What is it???
Dec 16, 1999

My sister was diagnosed in 1996, and after a terrible bout with crypt meningitis, has an undetectable vl and 300+ t cells. But she is subject to periodic bouts of unexplained fever, vomiting, and fatigue. It's so bad now (her fever spiked at 105) that she's in the hospital. All the cultures are negative, including the blood drawn directly from her Hickman catheter. In the past, they've forgotten about it when it passed, but it's worse now than ever. Any ideas? thank you.

Response from Dr. Feinberg

There are too many possibilities to give you a simple answer here. "Fever of unknown origin" is a medical condition that can be caused by a number of diseases, infectious and non-infectious, in both HIV+ and HIV- people. She needs to undergo a thorough evaluation, which includes tests other than cultures. There may be clues in her history and physical examination that can serve as a starting point for what else needs to be done to make a diagnosis.


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