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Immunity to Hepatitis B
Mar 1, 2000

RE: vaccination series for Hep B. In Hiv,and or HepC patients. Do we need a quantitative titre of over 10 for HepBsAB to prove immunity and defer vaccination or just a qualitative pos for AB. If the patient has had the disease and recovered, and is neg. for surface antigen and positive for surface antibody, is a Quantitative titre over 10 necessary to prove immunity? I have been assuming the quantitative test is necessary, while other Physicians are assuming immunity with a qualitative pos. for AB and a neg. AG.

Thank you

Response from Dr. Feinberg

Academicians might prefer the quantitative test, but in practice it is the qualitative test that is most accessible and is accepted as evidence of immunity. Remember, even in HIV-s the vaccine is not 100% efficacious.

Hep B Vaccination
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