|dapsone for PCP
Mar 15, 2001
Dear Dr. Feinberg, How does a physician determine what the first line of pharmacological treatment for PCP (pneumocystis carinii pneumonia) infection is? Is Dapsone usually the first choice, or does it depend on other interpatient variable factors? I'm just curious as to how many physicians actually prescribe Dapsone as the first line of treatment for PCP. Thanks.
Response from Dr. Feinberg
I'm not clear whether you are talking about prevention (prophylaxis) or treatment of established PCP. However, in both situations, dapsone is second choice after trimethoprim/sulfamethoxazole (Bactrim, Septra). For prevention, dapsone is used alone, but for treatment of active PCP, dapsone is used together with trimethoprim. This hierarchy of choices is based on the outcome of several clinical trials that were done for prevention and treatment in the late 80's-early 90's. TMP/SMX was consistently more effective for prevention and treatment in a number of primary and secondary analyses of the data. For patients who can't take TMP/SMX for whatever reason, dapsone or dapsone+trimethoprim is a reasonable alternative.
recurrent cryptococcal meningitis
Are animals a danger to HIV+s?
- Is Itchy Scrotum A Symptom Of HIV?
- How Likely Is It To Get AIDS From Sex With A Prostitute?
- Risk Of Blowjob From A Prostitute
- Red Spots After Giving Oral Sex What Are The Chances Of HIV
- White Bumps On Penis After Performing Oral Sex Worried I Have HIV
- Does Any Std Affect Your Urine Flow?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.