I have recently noticed that my vision seems to be blurring quite a bit. It's not a "blanket" blur -- rather, it seems to appear in crescent shapes just slightly to the left or right of my central line of vision. Also, my eyes just seem to ache more frequently. I have been somewhat medication non-compliant (feeling guilty) due to the side effects of the meds and my need to be able to take care of my children. I have been + for 15 years and full-blown for the last 6 or 7 years. My work requires a lot of reading and computer exposure. Last viral was about 40K and cd4 was around 300. Can you tell me what the symptoms of CMV are and what other possible conditions might be causing this problem?

CMV retinitis, the eye infection that can cause loss of vision, is extremely rare in people with 300 T cells. The only exception to this is when people recently begun on potent combination HIV meds have an abrupt increase in CD4 cells and the CMV infection that was 'incubating' when the HIV medicines were started has some unusual features, like occurring at CD4 cell counts above 50-75.

You need to do 2 things to set your mind at rest: you need to see an eye doctor experienced in treating HIV+s, and you need to talk with your primary caregiver who wrote your HIV prescriptions and get on a regimen that is manageable for you to take. The medicines aren't going to do you any good if they sit in the jar. There are lots of new approaches to simpler combinations that have fewer (or shorter-lasting) side effects.