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Lymphoma and Autoimmune disease
Feb 25, 2001
I have had a high ANA for 4 years and systemic symptoms. I was told I have MCTD. I have had a terrible rash on the scalp, pubic area and in areas over the body for 7 months. Diagnosis was folliculitus. No medication has helped as yet. Last week I noticed an enlarged lymph node. My DR found many nodes on each side of my neck. Both he and the ENT DR suspect lymphoma and I will have a node biopsy in one week. Can you tell me if there is a connection to MCTD and lymphoma. My DR said he thinks this node condition is the basis for all of my symptoms. I wonder if it is both conditions or if one thing lead to another. Your answer will be greatly appreciated.
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Response from Dr. Feinberg
Mixed connective tissue disease (MCTD) and other related autoimmune disorders can be associated with the subsequent devlopment of lymphoma. I cannot explain the mechanism for whay these things are associated, but it probably has something to do with the abnormal behavior of the immune system.
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