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Please Note: Due to volume considerations, not all questions can be answered. Questions most likely to be answered will be those of general interest to a broad group of visitors to this forum. Questions pertaining to a specific case; requests for diagnosis, medical advice, or second opinion; or requests for opinions about untested alternative therapies will generally not be answered.

Ask the Experts about Opportunistic Infections

 

High tryglicerides & hiv
Apr 12, 2003

Hello I have a zero vload for 6 months and my tcelss up from 198 to 536. I am currently taking epivir/sustiva/viread.

My latest blood work came up with a higher than normal tryglyceride level, around 256, but my cholesterol was normal. I work out 5 days a week and I am very fit. What does this all mean? I do eat like a pig, I love pies, cake, ice cream and stuff.

My question to you is, how do high trygli. levels affect me directly? Should I be concerned? what can I do to reduce those Trygli. levels? I heard about fish oil?

Also, sustiva, taking it for 6 months or more, and I can';t take it without temazepan to sleep othewise I wake up off and on during my sleep. I was told that this is a better option than switching me away from sustiva, your thoughts?

thank you so much

Steffan

Response from Mr. Vergel

Congratulations on your T cells and viral load!

High triglycerides may increase your heart disease and pancreatitis risks.

You may want to lower your simple carbohydrate intake (sweets, sugar, corn syrup, fructose, sodas, bottled fruit juices) to lower your triglycerides. Omega 3 oils at 1000 mg/day and L-Carnitine at 2000 mg/day have also shown to decrease triglycerides. I am glad you are exercising because that also helps!

Sustiva is an excellent drug but some people may not tolerate its effects on the CNS (central nervous system). Some people may have to switch to Viramune (another non-nuke in the same family). Viramune does not have the sleep disturbances but it can cause rash and increased liver enzymes in some patients. In a recent study (2NN) is was shown to have comparable efficacy than Sustiva.

Talk to your doctor about Sustiva's side effects and your options.



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