Treatment for HCV with low PCR and no liver disease
Aug 26, 2001
Hello Drs. thank you for your time. I have a few questions after reading the CDC update on HCV. I am a 33yr old female and was first tested positive with HCV, and negative for all other diseases, in 1994. I am still negative for all other diseases and I live in Southern California. Subsequently I have seen many diferent Drs, who have differently levels of knowledge of HCV. I am a little confused as to what tests are needed to follow the disease and if a liver biopsy is the only difinitive test. I have had normal liver enzymes every time I have been tested and the last HCV RNA by PCR quant was <2000 copies/ml and my HCV RNA log 10 was <3.3 log 10. My questions are: 1. what is considered a high viral load? (please explain both tests) 2. is there a more sensitive pcr test that will tell me exactley what my viral load is? (instead of just less than 2000) 3. should I have a liver biopsy, since the disease can be asymptomatic? 4. are there any trials being done on asymptomatic HCV positive people to irradicate the virus BEFORE it causes any disease? 5.lastly, what is the test called to findout what genotype of HCV I have, and is it necessary to know this for treatment.
Thank you again for your time, I am again going to a new Dr. and would like to tell him exactly what tests I need done and how frequently I will need them.
Response from Dr. Rodriguez-Torres
The test to check the genotype is exactly that:HCV genotype. There are tests that measure as low as 50iu or copies.The only test that gives definite information of the liver status, is the biopsy.Patients can have severe liver disease with normal blood tests.The biopsy can be done easily ,with sonographic guidance,its safe and ambulatory.If the disease is minimal ,patients can be observed and biopsy repeated every 3 years. There was a study of normal ALT patients ,with (Pegasys),but I am afraid, it closed enrrolment recently.
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Penis Discharge After Deep Kissing Worried I Have HIV
- Red Eyes After French Kissing Worried I Have HIV
- Testicular Pain After Anal Sex With Condom Does It Mean I Have HIV
- Vaginal Discharge After Fisting Worried I Have HIV
- White Bumps On Penis After Anal Sex Worried I Have HIV
- Physical Signs Of Std
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.