Aug 3, 2001
Dear Dr. Thanks for all the great help you are providing..this forum has helped a lot of people get through the mystery of these issues.
What is the significance of the change from e antigen to e antibody. Is one still infectious?
There seems to be a difference of opinion in the medical world.
Response from Dr. Dieterich
The seroconversion from hepatitis B e antigen to e antibody is generally considered an endpoint in clinical trials and usually means that the virus is no longer contagious. There is a rare condition called the pre core mutant where a mutation in the hepatitis B virus will still produce HBV DNA. That is not common in the US, but is fairly common in Asia. Hope that clears it up. DTD
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