Aug 3, 2001
Dear Dr. Thanks for all the great help you are providing..this forum has helped a lot of people get through the mystery of these issues.
What is the significance of the change from e antigen to e antibody. Is one still infectious?
There seems to be a difference of opinion in the medical world.
Response from Dr. Dieterich
The seroconversion from hepatitis B e antigen to e antibody is generally considered an endpoint in clinical trials and usually means that the virus is no longer contagious. There is a rare condition called the pre core mutant where a mutation in the hepatitis B virus will still produce HBV DNA. That is not common in the US, but is fairly common in Asia. Hope that clears it up. DTD
Using the DNA BY PCR for hiv testing
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