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neutropenia and chronic active HCV infection treatmentinfection
Jun 5, 2001

I was recently informed that chronic active hepatitis C can not be treated when occuring in an HIV infected person with lymph. T CD4+ count less than 200/mL or neuthrophils count less than 1000/mL.Is that a RULE or these are conditions which don't contraindicate treatment but turn it more prone of severe mielotoxicity?

Response from Dr. Rodriguez-Torres

We usually consider for treatment HIV coinfected patients,that have CD4 higher than 100,and total neutrophile count of 1500 or more.We also want patients to be well controlled from the HIV,and to be in stable therapy.The risk of decreases in CD4 and neutrophiles during therapy and infection is much greater in these patients and we are more cautious.



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