|Ribavirin and AZT/D4T
Jun 16, 2000
I heard that Ribavirin cancels out AZT and also D4T. The studies to this topic are all "in vitro". What really happens in case you take a HIV-Combo with AZT or D4T and INF+Riba? In an small study there where no negative effects seen, but could that be due to the INF that has also an effect on HIV? I am co-infected with HCV and HIV and I want to start with PEG-INF and Riba. I am on D4T,DDI,3TC and Indinavir since three years (VL 1500,CD4 600).
Does Riba really take out AZT/D4T? Or does it make these drugs less working? Is there a difference between AZT/Riba and D4T/Riba?
thank you in advance.
| Response from Dr. Dieterich
There have several small lab studies suggesting that ribavirin might compete for phosphorylation with AZT and D4T. At our site, at Johns Hopkins, in France and Spain, we now have data on over 100 people treated with ribavirin and despite taking AZT or D4T there have been no significant changes in HIV RNA. I would encourage you to be treated for both diseases and watch the levels carefully. DTD
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Average Life Expectancy With Hiv Usa
- Will A Shot Get Rid Of My Chlamydia?
- When You Have A Herpes Break Out How Long Does It Take To Get Blisters?
- What Medicine Is Used To Cure Gonorrhea?
- What Does A Sore Look Like When You Have Genital Herpes?
- What Antibiotics Can Be Used To Cure Chlamydia?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.