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Information Alk phos
Jul 1, 2013

My alt and billubrin is normal but alkaline phosphor is elevated 250. Hepa b& c is negative. What is reason.

Response from Dr. Taylor

Alkaline phosphatase comes mainly from the liver and bones. If this blood test is high and other liver blood tests are high, we consider that the elevated level likely comes from the liver; if the other liver blood tests are at normal levels, a bone sources is more likely. In some places you can test the level to see if it coms from the liver or bones.

If the alkaline phosphatase elevation comes from the liver, there are illness of the liver or the bile system that could be causing this. Certain drugs can cause this too, such as steroids. If the elevation comes from the bones, there is a list of bone-related issues that can contribute.

The level can also be high in pregnancy, from the placenta.

So ideally it would be great to have a doctor to evaluate this over time if the level remains high. A good medical and family history and physical exam are the places to start.



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