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recovery from acute HBV and Anti HBs titre
Dec 28, 2012

Dear Dr Taylor, I recovered from an acute episode of hep b and my serology now shows hbsag = neg, anti hbc = reactive, anti hbs = 15. I think that that means natural immunity has occured however I'm confused by a health advisor at the clinic who said that anti hbs <100 isn't protective and that I may need a vaccination. What do you think? Many thanks Michael

Response from Dr. Taylor

Dear Michael, I am glad that you recovered from your acute episode of hepatitis B. I think that natural immunity has occurred and you are protected from re-infection.

If you were acutely ill with hepatitis B and now have the blood test results you indicate, you do not need hepatitis B vaccination even if you have low titres of anti-HBs. Individuals in this situation are able to mount an effective immune response should they be re-exposed to hepatitis B. The levels of anti HBs are more relevant right after completing the vaccine series to see if one has developed an appropriate response.



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