3% of chronic HCV patients don't seroconvert?
May 19, 2012
I have read in several places that 97% of people will show HCV antibodies by 6 months, and other information that mentions 3% of chronic HCV patients never show antibodies. Also, I have seen several of your posts that state most people will show antibodies by 3 months, with some outliers taking up to 6 months. In what situations would someone not seroconvert at all or take longer than 6 months?
I had unprotected anal sex with another man over 7 months ago, and I have been freaking out since. I had negative HIV antibody tests at 2, 3, 6, and 7 months, and negative HCV antibody tests at 2 and 7 months. Also, negative for other STDs at 2 and 7 months. Is any more testing necessary? If both HIV and HCV antibody tests are negative at 7 months, is this completely conclusive?
Response from Dr. McGovern
Yes your testing is conclusive because both tests are negative. Great news!
You are correct in surmising that most people seroconvert by 12 weeks; a minority of patients take longer (up to six months). Anyone who takes longer than that are few in number. Having underlying HIV infection can delay antibody formation.
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