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Should I start treatment based on current test results?
Mar 11, 2012

Dear Doc, I have HBV for a while and just found out about it. My test results are

Hep B surface Antigen ( reactive ) Hep B surface Antibody ( non-reactive ) Hep B Core AB Total ( reactive ) Hep BE Antigen ( non-reactive ) Hep BE Antibody ( reactive ) Hep B virus DNA ( 17000 IU/ml ) Recent AST down from 145 to 63 u/l Recent ALT down from 276 to 128 u/l, tested 2wks apart, 5wks ago.

Based on my test results, should I start any treatment? What medicine would you recommend? At what DNA and ALT level should anyone start treatment? Can I transmit to my spouse (married 3 years and have unprotected sex, she's out of country and not available for test)? I'm not positive for HIV nor HCV. Thank you so much for your precious answers in advance.

Response from Dr. McGovern

I would hold off on any treatment since it sounds like this is a new diagnosis. Furthermore your liver function tests are coming down so I wonder if you are going to clear this infection especially with a viral load of only 17000.

I would simply follow up on the results.

When your wife comes back, it will be important to test. If your infection does not clear on its own, she will need protection with the HBV vaccine if she is negative.



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