Atripla vs. Norvir/Reyataz/Truvada
Dec 12, 2009
I have been on the Norvir, Reyataz, Truvada cocktail for one year now. I wanted to switch to Atripla. All of my friends are taking the one pill a day now and say its great. Would this jeopordize future regimens for me if I switch? I am tird of taking three pills a day and having to refrigerate Norvir. My doctor told me I could switch if I want. Any complications to the switch? Also, my GFR on my kidneys is 63 which is bordering kidney damage. My liver has high enzyme levels. I am 40yrs old and have been positive for three years. Am I screwed? Should I be very concerned? Could this be from the Truvada? Thank you.
Response from Dr. McGovern
If you have high liver enzyme levels, you should be tested for hepatitis B and C...If you do not have either infection, I would wonder about possible fatty liver -particularly if you have high triglycerides, obesity, or diabetes.
As for your kidneys, tenofovir (which is part of Atripla and Truvada) is somewhat of a concern...you should have your urine tested for protein excretion and have careful monitoring of your creatinine.
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