|unusual Hep C results
Oct 25, 2008
We have recently had two patients with strange Hep C results, I wonder if you can clarify. case one HIV+ve,IVDU HepCAb-ve until April this year. On his annual check tested HepCab+ve with a viral load of <30 copies indicating clearance. Repeated in September with a VL of 64 genotype 1. What does this indicate? Case 2 HIV+ve past IVDU of >15yrs who has been HepCPCR+ve previously on annual check of VL is now <30 copies, we repeated this to confirm and is still the same (without treatment). Is this common to spontaneouly clear without treating after all this time?
| Response from Dr. McGovern
Low levels of viremia can wax and wane. Since the test is based on RNA, which can degrade, sample handling is important. That is why I always double-check any non-detectable viral load.
Spontaneous clearance can occur even in chronic infection; however, this is distinctly uncommon and only reported in a few case reports. I have seen it myself.
Would follow again over time.
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