The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App 
Professionals >> Visit The Body PROThe Body en Espanol
Ask the Experts About

Hepatitis and HIV CoinfectionHepatitis and HIV Coinfection
Rollover images to visit our other forums!
  • Email Email
  • Glossary Glossary

HIV-Hep coinfection: test results definitive?
Jun 8, 2008

Thanks so much for the personal time that you continue to dedicate to answering questions through the forum.

In a potential case of HIV-Hepatitis coinfection (either HBV and/or HCV), and where the individual has shown both acute and then chronic Hepatitis symptoms, how definitive would you assess the following results to be:

HIV: negative antibody tests at 3, 9 and 13 weeks plus negative HIV RNA PCR at 16 weeks.

HBV: surface antibody (HBsAg) not detected at 9 and 13 weeks (all other antibody tests were undetected).

HCV: antibody not detected at 9 weeks and HCV RNA PCR tests negative at 9 and 13 weeks.

A couple of additional questions:

- is there any possibility that Hepatitis Delta (HDV) might impact any of these test results? (i.e. viral suppression). Despite all of the 'woo hoo' test result news listed above, I have shown a low lymphocyte count (and CD4 count of 484) at 15 I continue to get abdominal pain and other chronic Hepatitis symptoms.

And finally...can you give your honest view on the outlook for HIV/HBV/HCV triple infected patients infected during 2008. Do we believe that the antiviral treatments for HBV, and exciting protease inhibitors for HCV will significantly improve the outlook for triple infected patients?

Response from Dr. McGovern

Wow - lots of good questions.

1. First of all, most patients who get hepatitis are actually asymptomatic - eg, they have no symptoms. If they do have symptoms, they could be as non-specific as fatigue and loss of appetite.

2. You don't mention the nature of the exposure, but most testing for HIV goes out to six months. HBsAg is usually positive by 10 weeks. HCV antibody is usually positive in the majority of patients by 12 weeks although the testing is usually carried out at six months also. However, all of your results are very reassuring and will most likely hold over time.

3. I wouldn't consider delta without having HBsAg.

4. Yes, I do believe that the future is going to be bright for HCV and HBV therapeutics.

Untreated Hepatitis C
treatment for hep B carriers?

  • Email Email
  • Glossary Glossary



This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint