Aug 27, 2007
my brother recently diagnosed with Hep B in may 2007, HBsAg reactive at 291, HBeAg negative, Anti HBe reactive, HBV PCR DNA 30 copies/ml, ALT 43,GGT 289, Alp 204, total bili 0.44, Pt 9.9, Inr 0.94, liver uss normal, liver biopsy modified hepatic activity index 1/18, stage of fibrosis 2/6 Modified HAI grading 1/18 ( only portal inflammation) Modified staging fibrous expansion of most portal areas with or without short fibrous septa score 2/6 does he need treatment??
Response from Dr. McGovern
The HBV DNA level is low so I would recheck again to see if he is going to clear. I would also find out if there are any other causes for liver disease that could be modified - eg, excessive alcohol. The biopsy suggests that the disease activity is quiet (grade) but that there is some scarring (stage). The ALT also needs follow-up which is minimally abnormal, to see if that changes over time. However, his physician may have these data already if he has been in care for more than six months.
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