Apr 11, 2001
I recently had my genotype testing done which came back as a 2b, 1ml. copies. I understand this is a mid to high range viral load, and that genotype 2b is a better responder to combo. therapy. Can you tell me more? Thanks for any information you can give.
Response from Dr. Rodriguez-Torres
There are around 150 major sub-groups of HCV based on genetic variance.The main groups,1-6 ,are seen in different geographical regions.Gen 1 is the most common in U.S.Only 20-30% of cases are non 1.Genotype 2 patients, respond much better to combination treatment and to pegylated interferons.The preliminary data of Pegasys and Ribavirin showed a 100% end of treatment response.
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