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Hepatitis and HIV CoinfectionHepatitis and HIV Coinfection
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Incomplete Vaccination
Jun 5, 2007

I have a friend who did not complete his Hep B vaccination. Decades later, he was tested for the Hep B virus. The results were surface antigen positive, surface antibody negative, E antigen negative, E antibody positive. What does this mean? He is not actively contagious but can still infect others? Is this a result of his incomplete vaccination?

Response from Dr. McGovern

It appears that he did not receive his full immunization series, which is unfortunately common. He has evidence of chronic infection by the presence of his hepatitis B surface antigen. I cannot tell whether he is "contagious" or not unless he has testing for HBV DNA - the virus in the blood.

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