|Do I need PCR?
Aug 5, 2006
Doctor My boyfriend`s got abnormal ALT and GGT for many years. Hes 45 now and has been tested for hepatitis B and C several times in the past 15 years. Hes been hepatitis B vaccinated. All these tests came out negative. Hes German and got blood transfusion when he was 1 year old in Germany. Hes been followed by a great doctor whos specialized in liver disfunctions. All other tests as ultrassonography, ceruloplasmin, ferritin, etc turned out to be normal. My question is: should he be tested for hepatitis C by PCR method regarding that blood transfusion even though hes got all these negative tests (ELISA 3rd generation for hepatitis c)all these years? Thank you very much!! Im worried!!
| Response from Dr. McGovern
It sounds like your boyfriend has been tested extensively for hepatitis B and C viruses and is negative. I would not test any further since you have not mentioned any particular risk factors.
His minimally elevated ALT should be followed. His doctor may consider a liver biopsy at some point if these abnormalities persist or increase. I would be mainly concerned about fatty liver, if he has risk factors for this (diabetes, obesity, high cholesterol or triglycerides). Otherwise, his mildly elevated ALT could simply be a mild reaction to medications, alcohol, or even over the counter medications.
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