Jan 22, 2006
Does HCV viremia depend upon the immune competence of the host to enable its replication? In someone HIV/HCV co-infected, is HCV viral level generally higher or does not really matter...do the higher HCV levels make it tougher to cure in co-infection, or is it the damaged immune system that presents the challenge for cure in HIV/HCV co-infection? Thanks...
Response from Dr. McGovern
You have posed several excellent questions.
It has been observed in multiple studies that it appears that the HCV RNA load is higher in coinfected patients than in those with HCV alone. So it seems that the immune system may be important in controlling the level of virus.
This level of virus is important since treatment efficacy is based on getting that viral load down to non-detectable levels. Obviously this is harder if you are starting from a higher level. However, the level itself never discourages me from trying. Every individual is different and I follow viral loads on treatment to evaluate the patient's individual response before pre-judging the situation.
Get Email Notifications When This Forum Updates or Subscribe With RSS
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.