|ALT in immunocompromised
Nov 27, 2005
Why is ALT in HCV sometimes "in range" in immunocompromised? Is there a clear correlation between ALT and liver damage?
| Response from Dr. McGovern
The level of ALT reflects liver damage. However, it is important to realize that sometimes liver damage can exist with normal ALT - even in immunocompetent hosts. This has been well-described in patients with active hepatitis C (patients who are viremic) and normal ALT.
Whether a liver biopsy is needed or not depends on many different factors and should be discussed with your physician.
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