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please comment HBV
Sep 25, 2005

Dear doctor: 50 yrs old male; hbs ag positive,hbs ab <3.0 miu/ml,hbe ag negative, hbe ab positive, hbv dna (pcr) 13,700 copies/ml, alt 36, and ast 22. My family doctor didn't illustrate much to me about my illness and only gave prescription Lamivudine 100mg for half a year. I am ok or serious? Please comment. Thank You.

Response from Dr. McGovern

I usually like to get a liver biopsy before I start treatment to see how much inflammation and scarring there is. Your liver function tests are normal so your chance of responding to lamivudine is lower than a patient who has abnormal liver function tests. If there is not a lot of disease, I like to wait until the liver tests become more abnormal before starting treatment.



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