|Adoption - HBcAb positive
Jul 30, 2005
We received an adoption referral for our daughter, born in China 10/3/2003. She is listed as HBcAb Positive with the rest of Hep B tests listed as Negative.
HBsAg: Negative HBsAb: Negative HBeAg: Negative HBeAb: Negative HBcAb: Positive
The narrative says that she was diagnosed with Hepatitis B (don't know at what age probably at 6 months) but with a follow up hospital visit on 2/1/05 she only had "one positive" and "originally she had 3 positives". The narrative then states "conclusion of diagnosis that Hepatitis B has disappeared".
There was also a "HBV-DNA Virus DNA flourescent quantitative" test done 3/10/05 with a result of <5.0x10^2 copy/mL.
Does this mean that the little girl had Hep B and no longer has it? What does the HBV-DNA test show? And if she is free of Hep B and only has cAb from prior infection, can we vaccinate her once she is in US?
Thank you in advance for your help.
| Response from Dr. McGovern
From the blood tests we have it does appear that she was probably exposed to hepatitis B since "three tests" were positive and now she is core antibody positive. I would have thought her hepatitis surface antibody (protective antibodies) would have become positive and stayed positive too. However, she can safely receive hepatitis B vaccine when she gets to your country.
The negative surface antigen, negative e antigen and the hepatitis B DNA test are also reassuring that she does not have chronic disease and has cleared her infection.
Best of luck with your adoption proceedings. Dr. McGovern
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