Jul 21, 2005
I get blood tested for Hep A and the result was Hep A antiboy Total positive and Hep A antibody IgM negative . dose is it mean that i was infected in the past ? and dose the vaccinated person of Hep A will get the same result ? can you explain for me what is the deffrent between the vaccinated person and the infected person because some doctor say the positive antibody Total means that you was infected in the past because of the vaccination or you get infected from the food or water etc..can you explain for me this point. thank you very much .
Response from Dr. McGovern
You ask a very good question. Hepatitis A antibodies come in two types: IgM and IgG IgM indicates recent infection. IgG suggests past infection. Usually when hepatitis A screening is done, the "total" antibody refers to IgG; if the IgM is negative, recent infection is ruled out.
Vaccination can occasionally lead to false positive IgM.
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