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Hepatitis and HIV CoinfectionHepatitis and HIV Coinfection
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Is Hep B vaccine helpful
Jun 27, 2005

Hello Dr McGovern. You are an angel. I noticed you have taken time on weekends and even holidays to answer questions. I truly believe that you are not in medicine just to have a career but you are there to help people. And for that, I thank you and god bless you. I just have a quick question. Can people who are inactive HBsAg carriers benefit from regular HB vaccination? The reason why I ask this question is this. I was just diagnosed as an inactive carrier. HBsAg+, HBeAg-, HBeAb+, HBV DNA 800 copies/ml PCR. Knowing the stages of HB, I probably had millions of copies/ml at one point in the past. At that time my immune system kicked in and tried to get rid of it. It did a pretty good job because I now am inactive. I did a calculation based on MW of HBsAg being 24KD and the vaccine being 20mcg of HBsAg it comes out to roughly 5x10(13) copies/ml of body fluid for an average human. Isnt vaccination going to help some inactive carriers? Is the following study credible?


Response from Dr. McGovern

Immunizations are not routinely given to people for an inactive carrier state. I would discuss any preliminary study results with your physician to see what he or she would recommend since this is not yet done in clinical practice.

I am glad you find this website helpful!

Dr. McGovern

hepatitis b and pregnancy
lymphocytes and viral replication

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