The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App 
Professionals >> Visit The Body PROThe Body en Espanol
Ask the Experts About

Hepatitis and HIV CoinfectionHepatitis and HIV Coinfection
Rollover images to visit our other forums!
  • Email Email
  • Glossary Glossary

Pace of Progression by Grade
May 28, 2005

On a liver biopsy, how long does it usually take to progress from Grade I to Grade III? What is the difference between Grade and Stage?

Response from Dr. McGovern

Good question.

Grade refers to "necroinflammatory activity" - just hows many inflammatory cells are present; damage to the liver.

STage refers to "fibrosis" or scarring.

In my mind there can be a significant changes of grade that can occur quickly - depending on a binge of alcohol, exposure to a medication or herb that is toxic, or just progression of viral hepatitis which will take much longer - but no one knows exactly how long. It varies from individual to individual based on multiple factors.

Changes in stage usually occur over years but can be accelerated by other factors such as alcohol, fatty liver, or immunodeficiency.

Dr. McGovern

Do I need treatment?

  • Email Email
  • Glossary Glossary



This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint