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Hepatitis and HIV CoinfectionHepatitis and HIV Coinfection
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Mar 28, 2005

Hi, per your advise to me, i now have my DNA result. i wrote to you last Feb 26, 2005 and thanks for your immediate reply.

result of HBV DNA as follows : Remarks: HBV-DNA 358,000 COPIES/ML DETECTION LIMIT: 142,000-1,700,000,000 COPIES/ML

Kindly explain the result i got. Is my Hepa B becoming worst? for your reference here's my previous Hepa profile tests: Jan17,2003=HBsAg "R" Count 1.1230 CutOff 0.066 / AntiHBS "NR" count 0.2050 cuto off 0.55 Feb2,2004=HBsAg "R" count 3.5 cutoff 0.048 / IgM Anti A "NR": count 0.019 cutoff 0.326 / IgM Anti HBc "R": count 0.217 cutoff 0.868 / Anti HBs "N": count 1.0 IU/L cutoff 0-10 IU/L / HBeAg "NR": count 0.005 cutoff 0.053 / Anti HBe "R": count 0.056 cutoff 0.579 Nov2,2004= HBsAg "R": count 3.00 cutoff 0.105 / AntiHBs "NR": count 0.127 cutoff 0.370 / HBeAg "NR":count 0.027 cutoff 0.105 / AntiHBe "R": count 0.605 cutoff 0.970 / Anti HBs "R":count 0.520 cutoff 0.640 / Anti HAV IGM "NR": count 0.330 cutoff 0.810 Jan22,2005- HBsAg "R":count 2.0202 cutoff 0.399 / AntiHbs "NR":count 0.105 cutoff 0.310 / HBeAg "NR": count 0.120 cutoff 0.240 / Anti HBe "R":count 0.405 cutoff 0.715 / Anti HBc "R":count 0.680 cutoff 0.905 / Anti Hav IGM "NR": count 0.553 cutoff 0.740

What are the things i should ask to my doctor? What's the best medication to cure me? What's the next thing i should do?

thank you and more power


Response from Dr. McGovern

The HBV DNA level is very helpful. You have chronic infection with hepatitis B. You are a "Hepatitis B e antigen negative carrier" with low levels of viremia. But just the presence of virus indicates that hepatititis B is replicating in your blood.

If you have abnormal liver function tests, I would proceed with consideration of a liver biopsy and treatment. I recommend a liver biopsy to assess how much damage there is since treatment for patients with hepatitis B e antigen negative disease is longer than for patients with e antigen positive infection. Knowledge of the liver biopsy results will be helpful for decision making.

Good luck.

Dr. McGovern

HBV Vaccine
Viral Loads and Stages

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