|Hep B or something else?
Mar 27, 2005
Dear Dr. McGovern, This is my 3rd try. Please do address my question.
My husband has been Hep B carrier for many years - 15/20 yrs. 2 years ago his blood tests were normal except for the positive surface antigen. But this past december the ALT was elevated (61 on a scale of 2-60 u/l) and AST was normal. He went to his PCP who ordered somes tests and referred him to a GI specialist who ordered them again after a month. In both, the ALT was around the same, AST normal, the Hebp core and surface antigen were both positive, ANA screen was positive, Anti-nuclear Ab titer was 1:160 (normal was <1:40), ANA pattern speckled Hep B viral DNA < 100 (normal <100), <160 (normal <160 copies/ml). The AFP was negative/normal. His HAV ab Total and Igm and HCV ab were non-reactive. He is a vegetarian and non-drinker, non-smoker. He has taken painkillers often but not tylenol, mostly advil or motrin. Does not take any other medications / vitamins (except ensure)
What could such results mean? What would the next step be?
Response from Dr. McGovern
1. His hepatitis B profile is consistent with a chronic hepatitis B carrier. However, without a hepatitis B e antigen, E antibody, and HBV DNA viral load, I don't know if he is an inactive or active chronic carrier. 2. His ANA is suggestive also of autoimmune disease. This will need further follow-up by the hepatologist. 3. His liver enzymes are reassuring but will require further monitoring. If they change and become much more elevated, he may need a biopsy. 4. His lack of alcohol intake is a very good thing.
2nd attempt - please reply
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.